发明申请
US20180222987A1 ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO CD3 AND/OR CD123
审中-公开
基本信息:
- 专利标题： ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO CD3 AND/OR CD123
- 申请号：US15943685 申请日：2018-04-02
- 公开(公告)号：US20180222987A1 公开(公告)日：2018-08-09
- 发明人： Jana Albrecht , Cédric Barriere , Christian Beil , Jochen Beninga , Chantal Carrez , Stéphane Guerif , Katja Kroll , Christian Lange , Cendrine Lemoine , Wulf-Dirk Leuschner , Ercole Rao , Marion Schneider , Marie-Cécile Wetzel , Peter Wonerow
- 申请人： SANOFI
- 优先权： EP15305077.8 20150123
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; G01N33/574 ; C07K16/30 ; A61K39/00
摘要：
The present invention concerns antibody-like binding protein specifically binding to CD3 and binding specifically to at least one further antigen, for example CD123. The present invention also concerns antibody-like binding protein specifically binding to CD123 and binding specifically to at least one further antigen. The invention further concerns anti-CD3 antibodies and anti-CD123 antibodies. The invention also relates to pharmaceutical compositions comprising the antibody-like binding protein, anti-CD3 antibodies or anti-CD123 antibodies of the invention, and their use to treat cancer. The invention further relates to isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibody-like binding protein, anti-CD3 or anti-CD123 antibody and the use of said anti-CD123 antibody as a diagnostic tool.
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07K | 肽 |
| ------C07K16/00 | 免疫球蛋白，例如，单克隆或多克隆抗体 |
| --------C07K16/18 | .来自动物或人的抵抗物质 |
| ----------C07K16/28 | ..抗受体，细胞表面抗原或细胞表面决定因子 |