发明申请
US20180214550A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING NK CELL KILLING ACTIVITIES
审中-公开
基本信息:
- 专利标题： METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING NK CELL KILLING ACTIVITIES
- 申请号：US15741944 申请日：2016-07-07
- 公开(公告)号：US20180214550A1 公开(公告)日：2018-08-02
- 发明人： Armand BENSUSSAN , Martine BAGOT , Jérôme GIUSTINIANI , Yacine MERROUCHE , Adèle DE MASSON , Anne MARIE-CARDINE
- 申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITÉ PARIS DIDEROT - PARIS 7 , ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) , INSTITUT JEAN GODINOT
- 优先权： EP15306109.8 20150707
- 国际申请： PCT/EP2016/066099 WO 20160707
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K39/39 ; C07K16/28
摘要：
The present disclosure relates to methods and pharmaceutical compositions for enhancing NK cell killing activities. In particular, the disclosure relates to a method of enhancing NK cell killing activities in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a compound capable of stimulating CD245 on NK cells.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |
| --------A61K39/395 | .抗体；免疫球蛋白；免疫血清，例如抗淋巴细胞血清 |