基本信息:
- 专利标题： DE NOVO BINDING DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF
- 申请号：US15564430 申请日：2016-04-05
- 公开(公告)号：US20180209983A1 公开(公告)日：2018-07-26
- 发明人： David William LAFLEUR
- 申请人： SUBDOMAIN, LLC
- 申请人地址： US DC Washington
- 专利权人： Subdomain, LLC
- 当前专利权人： Subdomain, LLC
- 当前专利权人地址： US DC Washington
- 国际申请： PCT/US2016/026054 WO 20160405
- 主分类号： G01N33/574
- IPC分类号： G01N33/574 ; C07K16/28 ; C07K14/705 ; C07K16/10 ; A61K38/17
摘要：
Provided herein are de novo binding domain containing polypeptides (DBDpp) that specifically bind a target of interest. Nucleic acids encoding the DBDpp, and vectors and host cells containing the nucleic acids are also provided. Libraries of DBDpp, methods of producing and screening such libraries and the DBDpp identified from such libraries and screens are also encompassed. Methods of making and using the DBDpp are additionally provided. Such uses include, without limitation, affinity purification, and diagnostic and therapeutic applications.
IPC结构图谱:
| G | 物理 |
| --G01 | 测量；测试 |
| ----G01N | 借助于测定材料的化学或物理性质来测试或分析材料 |
| ------G01N33/00 | 利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料 |
| --------G01N33/48 | .生物物质，例如血、尿（G01N33/02至G01N33/14，G01N33/26，G01N33/44，G01N33/46优先；种子发芽能力测定入A01C1/02）；血球计数器 |
| ----------G01N33/483 | ..生物物质的物理分析 |
| ------------G01N33/53 | ...免疫测定法；生物特有的结合方法的测定；相应的生物物质 |
| --------------G01N33/574 | ....用于癌症 |