![TRANILAST COMPOSITIONS AND COCRYSTALS](/abs-image/US/2018/05/03/US20180118662A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: TRANILAST COMPOSITIONS AND COCRYSTALS
- 申请号:US15794530 申请日:2017-10-26
- 公开(公告)号:US20180118662A1 公开(公告)日:2018-05-03
- 发明人: Joanne HOLLAND , Christopher FRAMPTON
- 申请人: NUFORMIX LIMITED
- 申请人地址: GB Cambridge
- 专利权人: NUFORMIX LIMITED
- 当前专利权人: NUFORMIX LIMITED
- 当前专利权人地址: GB Cambridge
- 主分类号: C07C233/55
- IPC分类号: C07C233/55 ; C07C65/05 ; C07C235/38 ; C07C229/60 ; C07C275/02 ; C07C65/10 ; C07C65/03 ; C07D213/82 ; C07D275/06 ; C07C229/56
摘要:
New tranilast complexes and new tranilast cocrystals are disclosed. These include a 1:1 tranilast nicotinamide complex, a 1:1 tranilast nicotinamide cocrystal, a 1:1 tranilast saccharin complex, a 1:1 tranilast saccharin cocrystal, a 1:1 tranilast gentisic acid complex, a 1:1 tranilast gentisic acid cocrystal, a 1:1 tranilast salicylic acid complex, a 1:1 tranilast salicylic acid cocrystal, a 1:1 tranilast urea complex, a 1:1 tranilast urea cocrystal, a 1:1 tranilast 4-aminobenzoic acid complex, a 1:1 tranilast 4-aminobenzoic acid cocrystal, a 1:1 tranilast 2,4-dihydroxybenzoic acid complex and a 1:1 tranilast 2,4-dihydroxybenzoic acid cocrystal. Also disclosed are pharmaceutical compositions containing a tranilast complex or cocrystal of the invention and a pharmaceutically acceptable carrier. Methods of treatment using the tranilast complexes and cocrystals as well as the pharmaceutical compositions are disclosed.
公开/授权文献:
- US10150729B2 Tranilast compositions and cocrystals 公开/授权日:2018-12-11
IPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07C | 无环或碳环化合物 |
------C07C233/00 | 羧酸酰胺 |
--------C07C233/01 | .羧酰胺基的碳原子连接在氢原子或非环碳原子上 |
----------C07C233/02 | ..羧酰胺基的氮原子连接在氢原子或未取代烃基碳原子上 |
------------C07C233/53 | ...含有由六元芳环的碳原子连接在羧酰胺基的氮原子上的取代烃基 |
--------------C07C233/55 | ....羧酰胺基的碳原子连接在不饱和碳架的碳原子上 |