发明申请
US20180009839A1 2,2-DIFLUOROPROPIONAMIDE DERIVATIVES OF BARDOXOLONE METHYL, POLYMORPHIC FORMS AND METHODS OF USE THEREOF
审中-公开
基本信息:
- 专利标题： 2,2-DIFLUOROPROPIONAMIDE DERIVATIVES OF BARDOXOLONE METHYL, POLYMORPHIC FORMS AND METHODS OF USE THEREOF
- 申请号：US15622568 申请日：2017-06-14
- 公开(公告)号：US20180009839A1 公开(公告)日：2018-01-11
- 发明人： Eric ANDERSON , Xiaofeng LIU , Andrea DECKER
- 申请人： REATA PHARMACEUTICALS, INC.
- 申请人地址： US TX Irving
- 专利权人： REATA PHARMACEUTICALS, INC.
- 当前专利权人： REATA PHARMACEUTICALS, INC.
- 当前专利权人地址： US TX Irving
- 主分类号： C07J63/00
- IPC分类号： C07J63/00 ; A61K31/277 ; C07C255/47
摘要：
The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7, 8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.