A diaper with urine detection functionalities is provided. The diaper includes a urine isolation layer, an absorbent core layer, and an outer layer. A urine detection device is disposed between the urine isolation layer and the absorbent core layer. The isolation layer has an open end that is embedded in a sleeve of the absorbent core layer. The urine detection device comprises a detection circuit and a test paper composite. The test paper composite includes: a trace element test paper, an antibiotic test paper, and a urine routine test paper. Each test paper is made up of a plurality of test strips for detecting different elements. Each test strip produces results according to a different color indicator scheme.