发明申请
US20170305951A1 HETEROBIFUNCTIONAL INHIBITORS OF E-SELECTINS AND CXCR4 CHEMOKINE RECEPTORS
审中-公开
基本信息:
- 专利标题： HETEROBIFUNCTIONAL INHIBITORS OF E-SELECTINS AND CXCR4 CHEMOKINE RECEPTORS
- 申请号：US15531951 申请日：2015-12-01
- 公开(公告)号：US20170305951A1 公开(公告)日：2017-10-26
- 发明人： John L MAGNANI , Arun K. SARKAR , John M. PETERSON
- 申请人： GlycoMimetics, Inc.
- 申请人地址： US MD Rockville
- 专利权人： GlycoMimetics, Inc.
- 当前专利权人： GlycoMimetics, Inc.
- 当前专利权人地址： US MD Rockville
- 国际申请： PCT/US15/63191 WO 20151201
- 主分类号： C07H15/26
- IPC分类号： C07H15/26
摘要：
Compounds, compositions, and methods for treatment and/or prevention of cancer and inflammatory diseases, and for releasing cells such as stem cells (e.g., bone marrow progenitor cells) into circulating blood and enhancing retention of the cells in the blood are disclosed. For example, heterobifunctional compounds that inhibit both E-selectins and CXCR4 chemokine receptors are described and pharmaceutical compositions comprising at least one of the same.
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07H | 糖类；及其衍生物；核苷；核苷酸；核酸 |
| ------C07H15/00 | 含有直接连在糖化物基团的杂原子上的烃基或取代烃基的化合物 |
| --------C07H15/26 | .被杂环取代的无环或碳环基 |