基本信息:
- 专利标题： IMIDAZOLE AND THIAZOLE COMPOSITIONS FOR MODIFYING BIOLOGICAL SIGNALING
- 申请号：US15326821 申请日：2015-05-06
- 公开(公告)号：US20170210737A1 公开(公告)日：2017-07-27
- 发明人： Douglas Goetz , Stephen C. Bergmeier , Mark C. McMills , Crina M. Orac
- 申请人： Ohio University
- 申请人地址： US OH Athens
- 专利权人： Ohio University
- 当前专利权人： Ohio University
- 当前专利权人地址： US OH Athens
- 国际申请： PCT/US2015/029487 WO 20150506
- 主分类号： C07D417/14
- IPC分类号： C07D417/14 ; C07D413/04 ; C07D405/04 ; C07D417/04 ; C07D417/06 ; C07D277/36 ; C07D277/84 ; C07D233/84 ; C07D277/16
摘要：
Compounds having General Formula (I) or General Formula (II): in which R1 is chosen from C1 to C10 aliphatic or heteroaliphatic groups, optionally substituted with one or more aryl groups, substituted aryl groups, heteroaryl groups, substituted heteroaryl groups, or combination thereof; R2 is chosen from aromatic moieties, substituted aromatic moieties, heteroaromatic moieties substituted heteroaromatic moieties, and coumarin; R3 is chosen from —H, C1 to C10 aliphatic or heteroaliphatic groups, phenyl, or substituted phenyl, wherein the aliphatic or heteroaliphatic groups are optionally substituted with one or more phenyl groups, aryl groups, heteroaryl groups, substituted heteroaryl groups, or combination thereof, and wherein the aliphatic or heteroaliphatic groups are optionally bonded to R2 to form a ring; X is S or O; and Y is S or NH, may be used in pharmaceutical compositions that modify of biological signaling processes or as reagents for biological assays.
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D417/00 | 杂环化合物，含两个或更多个杂环、至少有1个环有氮原子和硫原子作为仅有的杂环原子，C07D415/00组不包含的 |
| --------C07D417/14 | .含有3个或更多个杂环 |