
基本信息:
- 专利标题: NEAR INFRARED LABEL AND METHODS OF USE THEREOF
- 专利标题(中):近红外线标签及其使用方法
- 申请号:US14889215 申请日:2014-05-08
- 公开(公告)号:US20160106867A1 公开(公告)日:2016-04-21
- 发明人: Arkady Mustaev , David S. Perlin , Laura Wirpsza
- 申请人: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY , NEW JERSEY INSTITUTE OF TECHNOLOGY
- 申请人地址: US NJ New Brunswick US NJ Newark
- 专利权人: Rutgers, The State University of New Jersey,New Jersey Institute of Technology
- 当前专利权人: Rutgers, The State University of New Jersey,New Jersey Institute of Technology
- 当前专利权人地址: US NJ New Brunswick US NJ Newark
- 国际申请: PCT/US2014/037339 WO 20140508
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; C07D401/12 ; G01N33/58 ; C07D405/14 ; C07D498/06 ; C07D219/08 ; C07K7/64
摘要:
The present invention provides compounds useful as novel near-infrared labels, compositions containing these compounds, and methods of using the near-infrared labels to identify targets in vitro, in situ and in vivo. The invention also provides small or large molecule conjugates between targeting agents and NIR labels, as well as methods and kits thereof, that can be used in diagnostics and treatment of diseases related to microbes in mammalian animals.
摘要(中):
本发明提供了可用作新型近红外标记的化合物,含有这些化合物的组合物,以及使用近红外标记在体外,原位和体内鉴定靶标的方法。 本发明还提供靶向剂和NIR标记之间的小分子或大分子缀合物,以及其可用于诊断和治疗哺乳动物中与微生物有关的疾病的方法和试剂盒。
公开/授权文献:
- US09700638B2 Near infrared label and methods of use thereof 公开/授权日:2017-07-11
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K49/00 | 体内试验用的配制品 |