![COMPOSITION FOR TREATING AND PREVENTING ISCHEMIC DAMAGE](/abs-image/US/2016/03/24/US20160082089A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: COMPOSITION FOR TREATING AND PREVENTING ISCHEMIC DAMAGE
- 专利标题(中):用于治疗和预防化疗损伤的组合物
- 申请号:US14785274 申请日:2014-04-18
- 公开(公告)号:US20160082089A1 公开(公告)日:2016-03-24
- 发明人: Sang Jae KIM
- 申请人: Sang Jae KIM , GEMVAX & KAEL CO., LTD.
- 申请人地址: KR Daejeon
- 专利权人: GEMVAX & KAEL CO., LTD.
- 当前专利权人: GEMVAX & KAEL CO., LTD.
- 当前专利权人地址: KR Daejeon
- 优先权: KR10-2013-0043636 20130419
- 国际申请: PCT/KR2014/003425 WO 20140418
- 主分类号: A61K38/45
- IPC分类号: A61K38/45 ; A23L1/03 ; C12N9/12
摘要:
The present disclosure relates to a composition for treating and preventing an ischemic injury. More particularly, it relates to a composition containing a peptide derived from a telomerase, which is effective in treating and preventing an ischemic injury. The peptide according to the present disclosure, a peptide having 80% or more sequence identity with the amino acid sequence of the peptide or a peptide which is a fragment thereof, has a superior effect of treating and preventing an ischemic injury. Accordingly, a composition containing the peptide may be effectively used for an ischemic injury, particularly for an ischemic-reperfusion injury.
摘要(中):
本公开涉及用于治疗和预防缺血性损伤的组合物。 更具体地,涉及含有源自端粒酶的肽的组合物,其有效治疗和预防缺血性损伤。 根据本公开的肽,与肽的氨基酸序列或作为其片段的肽具有80%以上序列同一性的肽具有治疗和预防缺血性损伤的优异效果。 因此,含有该肽的组合物可有效地用于缺血性损伤,特别是缺血再灌注损伤。
公开/授权文献:
- US09907838B2 Composition and methods for treating ischemic damage 公开/授权日:2018-03-06
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K38/00 | 含肽的医药配制品 |
--------A61K38/04 | .在完全确定的序列中最多有20个氨基酸的肽;其衍生物 |
----------A61K38/17 | ..来源于动物;来源于人类 |
------------A61K38/45 | ...转移酶(2) |