基本信息:
- 专利标题： PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES
- 专利标题（中）：包含单体的药物组合物
- 申请号：US14817286 申请日：2015-08-04
- 公开(公告)号：US20150368173A1 公开(公告)日：2015-12-24
- 发明人： Thomas CHEN , DANIEL LEVIN , SATISH PUPPALI
- 申请人： NEONC Technologies, Inc.
- 主分类号： C07C29/88
- IPC分类号： C07C29/88 ; C07C201/12 ; C07C67/14 ; C07C201/16
摘要：
The present invention provides a process for purifying a monoterpene or sesquiterpene having a purity greater than about 98.5% (w/w). The process comprises the steps of derivatizing the monoterpene (or sesquiterpene) to produce a monoterpene (or sesquiterpene) derivative, separating the monoterpene (or sesquiterpene) derivative, and releasing the monoterpene (or sesquiterpene) from the derivative. Also encompassed by the scope of the present invention is a pharmaceutical composition comprising a monoterpene (or sesquiterpene) having a purity greater than about 98.5% (w/w). The purified monoterpene can be used to treat a disease such as cancer. The present monoterpene (or sesquiterpene) may be administered alone, or may be co-administered with radiation or other therapeutic agents, such as chemotherapeutic agents.
摘要（中）：
本发明提供纯化大于约98.5％（w / w）的单萜或倍半萜的方法。 该方法包括衍生单萜（或倍半萜烯）以产生单萜（或倍半萜烯）衍生物，分离单萜（或倍半萜烯）衍生物和从衍生物中释放单萜（或倍半萜烯）的步骤。 包括本发明范围的药物组合物是包含纯度大于约98.5％（w / w）的单萜（或倍半萜烯）的药物组合物。 纯化的单萜可用于治疗癌症等疾病。 本单萜（或倍半萜烯）可以单独施用，或者可以与辐射或其它治疗剂如化学治疗剂共同施用。
公开/授权文献:
- US09480659B2 Pharmaceutical compositions comprising monoterpenes 公开/授权日：2016-11-01
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07C | 无环或碳环化合物 |
| ------C07C29/00 | 含羟基或氧—金属基连接碳原子的化合物的制备 |
| --------C07C29/64 | .用同时引入羟基和卤素 |
| ----------C07C29/88 | ..处理使至少一种化合物发生化学改性 |