发明申请
US20140171395A1 Tunable Nitric Oxide-Releasing Macromolecules Having Multiple Nitric Oxide Donor Structures
有权

基本信息:
- 专利标题: Tunable Nitric Oxide-Releasing Macromolecules Having Multiple Nitric Oxide Donor Structures
- 专利标题(中):具有多重一氧化氮供体结构的可调式一氧化氮释放大分子
- 申请号:US14184156 申请日:2014-02-19
- 公开(公告)号:US20140171395A1 公开(公告)日:2014-06-19
- 发明人: Mark Schoenfisch , Yuan Lu , Nathan Stasko , Jian Bao
- 申请人: The University of North Carolina at Chapel Hill , Novan, Inc.
- 申请人地址: US NC Chapel Hill US NC Durham
- 专利权人: The University of North Carolina at Chapel Hill,Novan, Inc.
- 当前专利权人: The University of North Carolina at Chapel Hill,Novan, Inc.
- 当前专利权人地址: US NC Chapel Hill US NC Durham
- 主分类号: A61K31/655
- IPC分类号: A61K31/655 ; C07C247/10 ; C07C281/20
摘要:
Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein.
摘要(中):
这里提供一氧化氮释放化合物,其包括相同类别的至少两种不同的NO供体官能团。 在一些实施方案中,这种释放氧化氮的化合物是大分子如树枝状聚合物和共缩合二氧化硅。 本文还提供药物组合物,伤口敷料,试剂盒和治疗方法。
公开/授权文献:
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K31/00 | 含有机有效成分的医药配制品 |
--------A61K31/655 | .偶氮(—NN—),重氮基(N2),氧化偶氮基(NON或N(O)—N),叠氮基(—N3)或重氮氨基的化合物 |