发明申请
US20120157514A1 OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN MODULATION OF SMALL NON-CODING RNAS
有权
基本信息:
- 专利标题： OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN MODULATION OF SMALL NON-CODING RNAS
- 申请号：US13412307 申请日：2012-03-05
- 公开(公告)号：US20120157514A1 公开(公告)日：2012-06-21
- 发明人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta
- 申请人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta
- 申请人地址： US CA San Diego
- 专利权人： REGULUS THERAPEUTICS INC.
- 当前专利权人： REGULUS THERAPEUTICS INC.
- 当前专利权人地址： US CA San Diego
- 主分类号： A61K31/712
- IPC分类号： A61K31/712 ; C12Q1/68 ; A61P37/00 ; C12N5/07
摘要：
Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.
公开/授权文献:
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/70 | .碳水化合物；糖；其衍生物 |
| ----------A61K31/7088 | ..含有3个或更多个核苷或核苷酸的化合物 |
| ------------A61K31/712 | ...含有修饰糖，即非核糖或2′脱氧核糖的核酸或寡核苷酸 |