![METHODS OF TREATING ANEURYSM](/abs-image/US/2012/03/15/US20120064088A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: METHODS OF TREATING ANEURYSM
- 专利标题(中):治疗神经病的方法
- 申请号:US13229093 申请日:2011-09-09
- 公开(公告)号:US20120064088A1 公开(公告)日:2012-03-15
- 发明人: Dai Yamanouchi , K. Craig Kent , Bo Liu
- 申请人: Dai Yamanouchi , K. Craig Kent , Bo Liu
- 申请人地址: US WI Madison
- 专利权人: Wisconsin Alumni Research Foundation
- 当前专利权人: Wisconsin Alumni Research Foundation
- 当前专利权人地址: US WI Madison
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61K31/675 ; A61P9/00 ; A61K31/663
摘要:
The present invention is directed to a method for treating aneurysms in vascular tissue. The method includes administering a bisphosphonate compound to a subject in an amount which is effective against the formation or progression of aneurysm, or which is effective to induce regression of an established aneurysm. In alternative methods, an anti-RANKL neutralizing antibody is administered to the subject to achieve analogous anti-aneurysm effect. The methods of particular advantage in the treatment of subjects having an abdominal aortic aneurysm, a relatively common, and life-threatening, condition.
摘要(中):
本发明涉及治疗血管组织中的动脉瘤的方法。 所述方法包括以对动脉瘤形成或进展有效的量给予受试者双膦酸盐化合物,或有效诱导建立的动脉瘤消退的量。 在替代方法中,向受试者施用抗RANKL中和抗体以获得类似的抗动脉瘤效应。 治疗具有腹主动脉瘤的受试者,相对常见的和危及生命的病症中特别有利的方法。
公开/授权文献:
- US08748410B2 Methods of treating aneurysm 公开/授权日:2014-06-10
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K39/00 | 含有抗原或抗体的医药配制品 |
--------A61K39/395 | .抗体;免疫球蛋白;免疫血清,例如抗淋巴细胞血清 |