发明申请
US20110171205A1 NOVEL 15571, 2465, 14266, 2882, 52871, 8203 AND 16852 MOLECULES AND USES THEREFOR
审中-公开

基本信息:
- 专利标题: NOVEL 15571, 2465, 14266, 2882, 52871, 8203 AND 16852 MOLECULES AND USES THEREFOR
- 专利标题(中):新型15571,2245,14266,2882,52871,8203和16852分子及其用途
- 申请号:US13012890 申请日:2011-01-25
- 公开(公告)号:US20110171205A1 公开(公告)日:2011-07-14
- 发明人: Martin R. Hodge , Clare M. Lloyd , Nadine S. Weich , Jose M. Lora , David White , Maria A. Glucksmann , Keith E. Robison , Inmaculada Silos-Santiago , Andrew D.J. Goodearl , Rory A.J. Curtis
- 申请人: Martin R. Hodge , Clare M. Lloyd , Nadine S. Weich , Jose M. Lora , David White , Maria A. Glucksmann , Keith E. Robison , Inmaculada Silos-Santiago , Andrew D.J. Goodearl , Rory A.J. Curtis
- 申请人地址: US MA Cambridge
- 专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Cambridge
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07H21/04 ; C12N5/00 ; C07K14/00 ; C07K16/18 ; C12P21/02 ; C12Q1/68 ; G01N33/53 ; A61K38/17 ; A61K31/7088 ; C12N15/11 ; C12N1/21 ; A61P25/00 ; A61P19/02 ; A61P25/28 ; A61P25/16 ; A61P25/18 ; A61P9/00 ; A61P9/04 ; A61P35/00 ; A61P3/10 ; A61P15/02
摘要:
The invention provides isolated nucleic acids molecules, designated 15571, 2465, 14266, 2882, 52871, 8203 or 16852 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 15571, 2465, 14266, 2882, 52871, 8203 or 16852 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 15571, 2465, 14266, 2882, 52871, 8203 or 16852 gene has been introduced or disrupted. The invention still further provides isolated 15571, 2465, 14266, 2882, 52871, 8203 or 16852 proteins, fusion proteins, antigenic peptides and anti-15571, 2465, 14266, 2882, 52871, 8203 or 16852 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要(中):
本发明提供分离的核酸分子,命名为15571,2465,14266,2882,52871,8203或16852核酸分子。 本发明还提供反义核酸分子,含有15571,2465,14266,2882,52871,8203或16852核酸分子的重组表达载体,已经引入表达载体的宿主细胞,以及非人类转基因动物,其中15571, 2465,14266,2882,52871,8203或16852基因已被引入或破坏。 本发明还进一步提供了分离的15571,2465,14266,2882,52871,8203或16852蛋白,融合蛋白,抗原肽和抗15571,2465,14266,2882,52871,8203或16852抗体。 还提供了利用本发明组合物的诊断和治疗方法。
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K39/00 | 含有抗原或抗体的医药配制品 |
--------A61K39/395 | .抗体;免疫球蛋白;免疫血清,例如抗淋巴细胞血清 |