![METHOD FOR PRODUCING BIPHENYL DERIVATIVE](/abs-image/US/2010/09/16/US20100230634A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: METHOD FOR PRODUCING BIPHENYL DERIVATIVE
- 专利标题(中):生产苯二酚衍生物的方法
- 申请号:US12377892 申请日:2007-10-12
- 公开(公告)号:US20100230634A1 公开(公告)日:2010-09-16
- 发明人: Tamio Hayashi , Jiro Nakatani
- 申请人: Tamio Hayashi , Jiro Nakatani
- 申请人地址: JP Otsu-shi, Shiga JP Urayasu-shi, Chiba
- 专利权人: Tamio HAYASHI,TORAY FINE CHEMICALS CO., LTD.
- 当前专利权人: Tamio HAYASHI,TORAY FINE CHEMICALS CO., LTD.
- 当前专利权人地址: JP Otsu-shi, Shiga JP Urayasu-shi, Chiba
- 优先权: JP2006-281677 20061016
- 国际申请: PCT/JP2007/069957 WO 20071012
- 主分类号: C07C1/26
- IPC分类号: C07C1/26 ; C07C17/00 ; C09K3/00
摘要:
A method produces a biphenyl derivative, with an industrially high yield and excellent productivity, by use of a raw material which is low in cost and toxicity. The method for producing the biphenyl derivative represented by Formula (1) is characterized in that a chlorine atom in a benzene derivative represented by Formula (2) reacts with magnesium metal to convert the benzene derivative into a Grignard reagent, and then the Grignard reagent is subjected to a coupling reaction in the presence of a catalyst and a dichloropropane: (wherein A represents at least one selected from alkyl groups, alkoxy groups, alkoxymethyl groups, a vinyl group, phenyl groups and chlorine, and n represents an integer of 1 to 4).
摘要(中):
通过使用低成本,低毒性的原料,能够得到工业上高产率,优异的生产率的联苯衍生物。 由式(1)表示的联苯衍生物的制造方法的特征在于,式(2)表示的苯衍生物中的氯原子与镁金属反应,将苯衍生物转化成格氏试剂,然后将格氏试剂 在催化剂和二氯丙烷的存在下进行偶联反应:(其中A表示选自烷基,烷氧基,烷氧基甲基,乙烯基,苯基和氯中的至少一种,n表示1〜 4)。
公开/授权文献:
- US08722942B2 Method for producing biphenyl derivative 公开/授权日:2014-05-13
IPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07C | 无环或碳环化合物 |
------C07C1/00 | 从一种或几种非烃化合物制备烃 |
--------C07C1/26 | .从只含卤素杂原子的有机化合物开始 |