A disposable ultrasonic surgical handle includes a disposable handle body that has a first handle body portion defining a handgrip and a second handle body portion connected to the first handle body portion, where the second handle body portion has a waveguide attachment dock exposed to the environment and having a first couple operable to connect an ultrasonic waveguide thereto and an aseptically sealable powered-ultrasonic-motion-generator assembly dock shaped to connect the ultrasonic waveguide in the attachment dock to an assembly within the assembly dock through the second handle body portion. The disposable ultrasonic surgical handle also includes a disposable compartment door movably connected to the second handle body portion to selectively expose the assembly dock to the environment, where the handle has an open position exposing the assembly dock to the environment and permitting entry and removal of the powered-ultrasonic-motion-generator assembly respectively into and from the assembly dock and a closed position aseptically sealing the assembly dock from the environment.