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基本信息:
- 专利标题: DETECTION METHODS USING TIMP1
- 专利标题(中):使用TIMP1的检测方法
- 申请号:US12052760 申请日:2008-03-21
- 公开(公告)号:US20080194043A1 公开(公告)日:2008-08-14
- 发明人: Jon H. ASTLE , Christopher C. BURGESS , Theodore J. CATINO , Poornima DWIVEDI , Maryanne HUNTRESS , Karen Anne JOHNSON , Marcia E. LEWIS , Peter J. MAIMONIS , Gary A. MOLINO , Susan H. MYEROW , Arunthathi THIAGALINGAM , Lisa Allyn BOARDMAN , Lawrence J. BURGART , Stephen N. THIBODEAU , Sheryl BROWN-SHIMER
- 申请人: Jon H. ASTLE , Christopher C. BURGESS , Theodore J. CATINO , Poornima DWIVEDI , Maryanne HUNTRESS , Karen Anne JOHNSON , Marcia E. LEWIS , Peter J. MAIMONIS , Gary A. MOLINO , Susan H. MYEROW , Arunthathi THIAGALINGAM , Lisa Allyn BOARDMAN , Lawrence J. BURGART , Stephen N. THIBODEAU , Sheryl BROWN-SHIMER
- 主分类号: G01N33/566
- IPC分类号: G01N33/566
摘要:
The present invention relates to a method for detecting the presence of colorectal cancer in an individual, wherein colorectal cancer is detected by detecting the presence of Reg1α or TIMP1 nucleic acid or amino acid molecules in a clinical sample obtained from the patient, wherein Reg1α or TIMP1 expression is indicative of the presence of colorectal cancer. The invention further relates to a method for detecting the presence of colorectal cancer in an individual, wherein colorectal cancer is detected by detecting the presence of Reg1α or TIMP1 nucleic acid or amino acid molecules in a clinical sample, in addition to detecting the presence of one or more additional colorectal cancer associated markers.
摘要(中):
本发明涉及用于检测个体中结肠直肠癌存在的方法,其中通过检测从患者获得的临床样品中Reg1alpha或TIMP1核酸或氨基酸分子的存在来检测结肠直肠癌,其中Reg1alpha或TIMP1 表达是指示结肠直肠癌的存在。 本发明还涉及一种用于检测个体中结肠直肠癌存在的方法,其中通过检测临床样品中Reg1al或TIMP1核酸或氨基酸分子的存在来检测结肠直肠癌,另外检测一种 或更多的结肠直肠癌相关标志物。
IPC结构图谱:
G | 物理 |
--G01 | 测量;测试 |
----G01N | 借助于测定材料的化学或物理性质来测试或分析材料 |
------G01N33/00 | 利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料 |
--------G01N33/48 | .生物物质,例如血、尿(G01N33/02至G01N33/14,G01N33/26,G01N33/44,G01N33/46优先;种子发芽能力测定入A01C1/02);血球计数器 |
----------G01N33/483 | ..生物物质的物理分析 |
------------G01N33/53 | ...免疫测定法;生物特有的结合方法的测定;相应的生物物质 |
--------------G01N33/566 | ....利用了特定的载体或接受体蛋白质作为配体结合试剂 |