发明申请
US20070287991A1 Devices and methods for detection of markers of axial pain with or without radiculopathy
审中-公开
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基本信息:
- 专利标题: Devices and methods for detection of markers of axial pain with or without radiculopathy
- 专利标题(中):用于检测具有或不具有神经根病变的轴向疼痛标记物的装置和方法
- 申请号:US11449530 申请日:2006-06-08
- 公开(公告)号:US20070287991A1 公开(公告)日:2007-12-13
- 发明人: William F. McKay , Jeffrey M. Gross , Hai Trieu , Josee Roy , Susan J. Drapeau , Michael J. Schendel , Andrew J. Lowenthal Walsh
- 申请人: William F. McKay , Jeffrey M. Gross , Hai Trieu , Josee Roy , Susan J. Drapeau , Michael J. Schendel , Andrew J. Lowenthal Walsh
- 主分类号: A61K9/22
- IPC分类号: A61K9/22
摘要:
The invention provides devices and related methods and composition useful for diagnosis and monitoring the pain generator(s) of axial pain with or without radiculopathy and methods for screening test compounds potentially useful for treating axial pain with or without radiculopathy. Alternatively, degenerated discs can be monitored and treated before occurrence of a pathological pain condition. Pain markers and markers of degenerating disc include markers of neuronal, vascular, immune and matrix elements.
摘要(中):
本发明提供了用于诊断和监测具有或不具有神经根病变的轴向疼痛的疼痛发生器的装置和相关方法和组合,以及用于筛选潜在地可用于治疗或不发生神经根病变的轴向疼痛的测试化合物的方法。 或者,可以在发生病理性疼痛状况之前监测和治疗退化的椎间盘。 退行性椎间盘的疼痛标志物和标志物包括神经元,血管,免疫和基质元件的标记物。
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K9/00 | 以特殊物理形状为特征的医药配制品 |
--------A61K9/10 | .分散液;乳剂 |
----------A61K9/22 | ..持续释放或间断释放型 |