基本信息:
- 专利标题： METHODS FOR ASSESSMENT OF CARDIOVASCULAR DISEASE RISK
- 专利标题（中）：评估心血管疾病风险的方法
- 申请号：US11278651 申请日：2006-04-04
- 公开(公告)号：US20070238183A1 公开(公告)日：2007-10-11
- 发明人： Robert Stout
- 申请人： Robert Stout
- 主分类号： G01N33/92
- IPC分类号： G01N33/92
摘要：
Methods are provided for more accurately assessing cardiovascular disease (CVD) risk factors in individuals or populations, using a bimodal analysis including cholesterol-based CVD risk markers together with serum triglyceride levels. Preferably, if a CVD marker (e.g., the ratio of total cholesterol to HDL) yields high risk factors, these factors may be adjusted in inverse relationship to serum triglyceride concentrations. If for example a given marker gives initial risk factors substantially equivalent to relative risk factors of about 1.5 or above, then the initial risk factors can be decreased if serum triglyceride levels are high, or increased if serum triglyceride levels are low. The invention is particularly useful for accurately assigning relative risk of mortality in the life insurance industry, and in decisions about prescribing or withholding medications.
摘要（中）：
提供了更准确地评估个体或群体中心血管疾病（CVD）危险因素的方法，使用双峰分析，包括基于胆固醇的CVD风险标志物以及血清甘油三酯水平。 优选地，如果CVD标记（例如，总胆固醇与HDL的比率）产生高危因素，则这些因子可以与血清甘油三酯浓度成反比关系。 如果例如给定的标记给出基本上等于约1.5或更高的相对危险因素的初始危险因素，则如果血清甘油三酯水平高，则可以降低初始危险因素，或者如果血清甘油三酯水平低，则可增加初始危险因素。 本发明对于在人寿保险行业中准确地分配相对死亡风险以及关于处方或扣留药物的决定特别有用。