基本信息:
- 专利标题： Suturable adhesion-preventing membrane
- 专利标题（中）：可固化防粘膜
- 申请号：US11255922 申请日：2005-10-24
- 公开(公告)号：US20060041320A1 公开(公告)日：2006-02-23
- 发明人： Kazuhisa Matsuda
- 申请人： Kazuhisa Matsuda
- 优先权： JP11-12625 19990121; JP11-85477 19990329
- 主分类号： A61F2/02
- IPC分类号： A61F2/02 ; C12N5/08
摘要：
A suturable adhesion-preventing membrane has high suture strength, good biocompatibility, decomposition and absorption in a living body, sufficient adhesion-preventing effect, and desirable guided tissue regeneration. The membrane is composed of at least one non-woven fabric layer made of collagen fibers, or a laminated membranous substance consisting of at least one non-woven fabric layer made of collagen fibers and at least one sponge layer made of collagen, and a coating layer of gelatin or hyaluronic acid on the surface or surfaces of the above membrane. Preferably, the membrane comprises one to six compressed cross-linked collagen non-woven fabric layers wherein a layer has a fibers having a fiber diameter of 0.05 mm to 1.0 mm, a bulk density of 5.0×10−4 to 5 g/cm3 and a thickness of 0.1 mm to 50 mm, and a coating layer containing gelatin or hyaluronic acid and having a thickness of 0.05 mm to 20 mm, wherein the coating layer covers one or both sides or a part or whole of the surface of the membrane.
摘要（中）：
可缝合的防粘膜在生物体中具有高缝合强度，良好的生物相容性，分解和吸收，足够的防粘连效果和期望的引导组织再生。 该膜由至少一层由胶原纤维制成的无纺织物层或由至少一层由胶原纤维制成的无纺布层和至少一层由胶原制成的海绵层组成的层状膜状物质和涂层 明胶或透明质酸层在上述膜的表面或表面上。 优选地，膜包含一至六个压缩的交联胶原蛋白无纺织物层，其中一层具有纤维直径为0.05mm至1.0mm，体积密度为5.0×10 -4 至5g / cm 3，厚度为0.1mm至50mm，以及含有明胶或透明质酸的涂层，其厚度为0.05mm至20mm，其中涂层覆盖一个或多个 两侧或膜的表面的一部分或全部。