基本信息:
- 专利标题： Biomarkers for liver diseases and method for using the same
- 专利标题（中）：肝脏疾病生物标志物及其使用方法
- 申请号：US11013684 申请日：2004-12-17
- 公开(公告)号：US20050136489A1 公开(公告)日：2005-06-23
- 发明人： Tzu-Ling Tseng , Ping-Fu Cheng
- 申请人： Tzu-Ling Tseng , Ping-Fu Cheng
- 申请人地址： TW Hsin Chu TW Hsinchu
- 专利权人： Industrial Technology Research Institute,Industrial Technology Research Institute
- 当前专利权人： Industrial Technology Research Institute,Industrial Technology Research Institute
- 当前专利权人地址： TW Hsin Chu TW Hsinchu
- 优先权： TW92136309 20031219
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07K14/47 ; C07K16/18 ; G01N21/78 ; G01N33/543 ; G01N33/567 ; G01N33/574 ; G01N33/68
摘要：
Biomarkers for liver diseases and method for using the same are provided. For detecting liver cirrhosis and liver cancer, the biomarkers are selected from any one of the amino acid sequences with SEQ ID NO:1 to SEQ ID NO:24 or derivatives or fragments or variants or the combination thereof or the antibodies against the amino acid sequences. Then the biomarkers are further developed into detection kits, such that by detecting the existence of autoantibodies or autoantigens in screened specimens, liver diseases are detected with higher accuracy and sensitivity.
摘要（中）：
提供肝脏疾病的生物标志物及其使用方法。 为了检测肝硬化和肝癌，生物标志物选自SEQ ID NO：1至SEQ ID NO：24的任一氨基酸序列或衍生物或片段或变体或其组合或针对氨基酸序列的抗体 。 然后生物标志物进一步发展为检测试剂盒，通过检测筛选标本中自身抗体或自身抗原的存在，以更高的准确度和灵敏度检测肝脏疾病。