基本信息:
- 专利标题： Competent bacteria
- 专利标题（中）：感染细菌
- 申请号：US10655914 申请日：2003-09-05
- 公开(公告)号：US20050032225A1 公开(公告)日：2005-02-10
- 发明人： Frederick Blattner , Gyorgy Posfai , Christopher Herring , Guy Plunkett , Jeremy Glasner , Trevor Twose
- 申请人： Frederick Blattner , Gyorgy Posfai , Christopher Herring , Guy Plunkett , Jeremy Glasner , Trevor Twose
- 主分类号： C12N1/08
- IPC分类号： C12N1/08 ; C12N1/21 ; C12N15/74
摘要：
The present invention discloses that a bacterium having a genome that is genetically engineered to be at least 10% smaller than the genome of its native parent strain has better transformation competence. Specific E. coli strains, having significantly reduced genome sizes, are disclosed which are highly transformation competent. A medium and methodology is taught which enables transformation efficiencies to be increased further.
摘要（中）：
本发明公开了一种具有遗传工程化至少比其天然母本基因组的基因组小10％的基因组的细菌具有更好的转化能力。 公开了具有显着降低的基因组大小的特异性大肠杆菌菌株，其具有高度转化能力。 介绍了一种可以进一步提高转换效率的介质和方法。
公开/授权文献:
- US07303906B2 Competent bacteria 公开/授权日：2007-12-04