![Compositions and methods for treating or preventing memory impairment](/abs-image/US/2004/03/04/US20040044023A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: Compositions and methods for treating or preventing memory impairment
- 专利标题(中):用于治疗或预防记忆障碍的组合物和方法
- 申请号:US10231361 申请日:2002-08-30
- 公开(公告)号:US20040044023A1 公开(公告)日:2004-03-04
- 发明人: Marc Cantillon
- 主分类号: A61K031/55
- IPC分类号: A61K031/55 ; A61K031/4745 ; A61K031/473 ; A61K031/401 ; A61K031/366 ; A61K031/225
摘要:
The present invention relates to pharmaceutical compositions for treatment or prevention of memory impairment which comprise a cholinesterase inhibitor and at least one other pharmacologically active agent selected from HMG-CoA reductase inhibitors, cholesterol absorption inhibitors, gamma or beta secretase inhibitors, NMDA antagonists, muscarinic receptor agonists and nicotinic receptor agonists. Additionally, the present invention relates to the use of these pharmaceutical compositions to treat or prevent memory impairment in a mammal, such as a human.
摘要(中):
本发明涉及用于治疗或预防记忆障碍的药物组合物,其包含胆碱酯酶抑制剂和至少一种其它药理活性剂,其选自HMG-CoA还原酶抑制剂,胆固醇吸收抑制剂,γ或β分泌酶抑制剂,NMDA拮抗剂,毒蕈碱受体 激动剂和烟碱受体激动剂。 另外,本发明涉及这些药物组合物在哺乳动物(例如人)中治疗或预防记忆障碍的用途。