![Manufacture of improved support matrices](/abs-image/US/2003/07/31/US20030144127A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: Manufacture of improved support matrices
- 专利标题(中):改进的支撑矩阵的制造
- 申请号:US10168709 申请日:2002-09-09
- 公开(公告)号:US20030144127A1 公开(公告)日:2003-07-31
- 发明人: Eva Berggren , Dag Lindstrom
- 优先权: SE9904801-0 19991228
- 主分类号: B01J019/00
- IPC分类号: B01J019/00
摘要:
A method for the production of a cross-linked support matrix that in form of a bed will permit liquid flow velocities above 5 cm/h, preferably above 50 cm/h, to pass through the bed. The method is characterized in that it comprises the steps: (a) providing a starting support matrix that has pendent unsaturated groups, and (b) subjecting said starting support matrix to electron beam or gamma-ray irradiation. The use of a cross-linked support matrix produced by a method comprising the steps of: (a) providing a starting support matrix that has pendent unsaturated groups, and (b) subjecting said starting support matrix to electron beam or gamma-ray irradiation as a support matrix in liquid chromatography, cell culturing, step-wise solid phase synthesis of organic compounds, running catalytic reactions by the use of a solid phase bound catalyst.
摘要(中):
用于生产以床形式的交联载体基质的方法将允许高于5cm / h,优选地高于50cm / h的液体流速通过床。 该方法的特征在于其包括以下步骤:(a)提供具有侧链不饱和基团的起始载体基质,和(b)使所述起始载体基质经受电子束或γ射线照射。 使用通过包括以下步骤的方法产生的交联载体基质:(a)提供具有侧链不饱和基团的起始载体基质,和(b)使所述起始载体基质进行电子束或γ射线照射, 液相色谱法中的支持基质,细胞培养,有机化合物的逐步固相合成,通过使用固相结合的催化剂进行催化反应。
公开/授权文献:
- US07208532B2 Manufacture of improved support matrices 公开/授权日:2007-04-24