发明申请
US20030105100A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
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基本信息:
- 专利标题： Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
- 申请号：US10155451 申请日：2002-05-23
- 公开(公告)号：US20030105100A1 公开(公告)日：2003-06-05
- 发明人： James A. Sikorski , Richard C. Durley , Deborah A. Mischke , Emily J. Reinhard , Yvette M. Fobian , Michael B. Tollefson , Lijuan Wang , Margaret L. Grapperhaus , Brian S. Hickory , Mark A. Massa , Monica B. Norton , William F. Vernier , Barry L. Parnas , Michele A. Promo , Ashton T. Hamme , Dale P. Spangler , Melvin L. Rueppel
- 申请人： G.D. Searle & Co.
- 申请人地址： IL Chicago
- 专利权人： G.D. Searle & Co.
- 当前专利权人： G.D. Searle & Co.
- 当前专利权人地址： IL Chicago
- 主分类号： C07D43/02
- IPC分类号： C07D43/02 ; C07D41/02 ; A61K031/53 ; A61K031/506 ; A61K031/501 ; A61K031/497
摘要：
The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases.