基本信息:
- 专利标题： DNA aptamers and use thereof for the treatment of cancer
- 申请号：US17413550 申请日：2019-12-16
- 公开(公告)号：US12077760B2 公开(公告)日：2024-09-03
- 发明人： Gabriel Lopez-Berestein , Paola Amero , Cristian Rodriguez-Aguayo , Rahul Mitra , Anil K. Sood , Vittorio De Franciscis , David Volk , Lokesh Ganesh L. Rao
- 申请人： Board of Regents, The University of Texas System , Consiglio Nazionale delle Ricerche
- 申请人地址： US TX Austin
- 专利权人： Board of Regents, The University of Texas System,Consiglio Nazionale delle Ricerche
- 当前专利权人： Board of Regents, The University of Texas System,Consiglio Nazionale delle Ricerche
- 当前专利权人地址： US TX Austin; IT Rome
- 代理机构： Parker Highlander PLLC
- 国际申请： PCT/US2019/066654 2019.12.16
- 国际公布： WO2020/124095A 2020.06.18
- 进入国家日期： 2021-06-12
- 主分类号： C12N15/115
- IPC分类号： C12N15/115 ; A61K31/337 ; A61K33/243 ; A61P35/00
摘要：
Provided herein are DNA aptamers targeting AXL receptor kinase. The DNA aptamers may comprise a thiophosphate backbone and be chemically modified. Further provided herein are methods of use thereof for the treatment of a disease or disorder, such as cancer.
公开/授权文献:
- US20220380766A1 DNA APTAMERS AND USE THEREOF FOR THE TREATMENT OF CANCER 公开/授权日：2022-12-01