基本信息:
- 专利标题: 用於分子及細胞成像之摻雜矽空位之奈米鑽石
- 专利标题(英):Silicon-vacancy-doped nanodiamonds for molecular and cellular imaging
- 专利标题(中):用于分子及细胞成像之掺杂硅空位之奈米钻石
- 申请号:TW104105723 申请日:2015-02-17
- 公开(公告)号:TW201536256A 公开(公告)日:2015-10-01
- 发明人: 阿寇斯塔 維克多 瑪賽爾 , ACOSTA, VICTOR MARCEL , 巴札札 維克朗 星 , BAJAJ, VIKRAM SINGH , 荷米克 安德魯 , HOMYK, ANDREW , 彼特斯 艾瑞克 , PEETERS, ERIC , 湯普森 傑森 唐諾德 , THOMPSON, JASON DONALD
- 申请人: 咕果公司 , GOOGLE INC.
- 专利权人: 咕果公司,GOOGLE INC.
- 当前专利权人: 咕果公司,GOOGLE INC.
- 代理人: 陳長文
- 优先权: 14/186,937 20140221
- 主分类号: A61B5/1455
- IPC分类号: A61B5/1455 ; G01N33/48
An imaging agent for detecting analytes in a biological environment includes functionalized, silicon vacancy center-containing nanodiamonds. Individual nanodiamonds of the imaging agent include at least one silicon vacancy center. The at least one silicon vacancy center can emit light having a wavelength in a narrow band in response to illumination having any wavelength in a wide range of wavelengths. The nanodiamonds are functionalized to selectively interact with an analyte of interest. The nanodiamonds can additionally include other color centers, and the imaging agent can include a plurality of sets of nanodiamonds having detectably unique ratios of silicon vacancy centers to other color centers. The silicon vacancy centers in the nanodiamonds can have a preferred orientation enabling orientation tracking of individual nanodiamonds or other applications. A method for detecting properties of the analyte of interest by interacting with the imaging agent is also provided.
公开/授权文献:
- TWI572329B 用於分子及細胞成像之摻雜矽空位之奈米鑽石 公开/授权日:2017-03-01
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61B | 诊断;外科;鉴定 |
------A61B5/00 | 用于诊断目的的测量;人的辨识 |
--------A61B5/145 | .测量体内血液特性,例如,气体浓度、pH值 |
----------A61B5/1455 | ..用光学传感器,如分光光度血氧计 |