发明专利
TW200942230A 2-胺基-2苯基-烷醇衍生物,其製造方法,以及含此衍生物之醫藥組成物 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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基本信息:
- 专利标题: 2-胺基-2苯基-烷醇衍生物,其製造方法,以及含此衍生物之醫藥組成物 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
- 专利标题(英):2-amino-2-phenyl-alkanol derivatives, their preparation and pharmaceutical compositions containing them
- 专利标题(中):2-胺基-2苯基-烷醇衍生物,其制造方法,以及含此衍生物之医药组成物 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
- 申请号:TW098101864 申请日:2009-01-19
- 公开(公告)号:TW200942230A 公开(公告)日:2009-10-16
- 发明人: 博舒特 傑恩 , 迪尼 克理斯多夫 , 德尼斯 艾力克斯
- 申请人: 歐羅克斯生物科技公司 , 艾力克斯 德尼斯
- 申请人地址: OROXCELL 法國 FR; DENIS ALEXIS 法國 FR
- 专利权人: 歐羅克斯生物科技公司,艾力克斯 德尼斯
- 当前专利权人: 歐羅克斯生物科技公司,艾力克斯 德尼斯
- 当前专利权人地址: OROXCELL 法國 FR; DENIS ALEXIS 法國 FR
- 代理人: 洪澄文
- 优先权: 法國 08/00521 20080131 美國 61/084,829 20080730
- 主分类号: A61K
- IPC分类号: A61K ; C07C
2-amino-2-phenyl-alkanol ester derivatives of general formula (I) in which: R1 is H, straight or branched 1 to 4C alkyl, straight or branched 2 to 4C alkyl substituted by OH, alkoxy, alkylthio, acyloxy, NH2, alkylamino, dialkylamino, alkylcarbamoyloxy, alkoxycarbonylamino, ureido or alkylureido, R2 is a -CO-R radical in which R is H, alkyl, aryl, heterocyclyl, benzyl or heterocyclylmethyl, or R2 is a - CO-Y-R4 radical for which Y is -0-, -S-, -NH-, -Nalk- for which alk is straight or branched (1 to 4C) alkyl, and R4 is alkyl, aryl, aralkyl or heterocyclylalkyl, capable of being substituted by one or more halogen atoms or OH radicals, straight or branched (1 to 4C) alkyl, alkoxy, alkylthio, acylaminoalkylthio, alkoxycarbonyl or acylamino (1 to 4C) straight or branched, or oxo, or capable of being substituted by R5COO- in which R5 is alkyl optionally substituted by benzyloxycarbonylamino, acylamino or by an amino acid residue, or represents an heterocyclyl radical, or R2 is alkyl (2 to 4C) substituted by OH, alkoxy, alkylthio, acyloxy, NH2, alkylamino, dialkylamino optionally forming, with the nitrogen atom to which they are attached, a 5- or 6-member heterocycle optionally having another heteroatom (0 or N), or substituted by alkylcarbamoyloxy, alkoxycarbonylamino, ureido or alkylureido, it being understood that said straight or branched substituted alkyl radical comprises at least 2C between > N-R2 and the substituent; and R3 is alkyl (1 to 4C) straight or branched unless specifically mentioned, alkyl or acyl are straight or branched (1 to 7C), in their R or S forms or their mixtures, as well as their pharmaceutically acceptable salts when these exist.
公开/授权文献:
- TWI393561B 2-胺基-2苯基-烷醇,其製造方法,以及含此化合物之醫藥組成物 公开/授权日:2013-04-21
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |