基本信息:
- 专利标题： 스쿠알렌 생산이 증대된 균주 및 이를 이용한 스쿠알렌 생산방법
- 专利标题（英）：Strain with increased squalene production and method for producing squalene using the same
- 申请号：KR20190093437 申请日：2019-07-31
- 公开(公告)号：KR102176556B1 公开(公告)日：2020-11-09
- 发明人： LEE JU YOUNG , KIM JAE EUNG , SON SOHEE
- 申请人： 한국화학연구원
- 申请人地址： , Gajeong-ro, Yuseong...
- 专利权人： 한국화학연구원
- 当前专利权人： 한국화학연구원
- 当前专利权人地址： , Gajeong-ro, Yuseong...
- 代理人： 특허법인한얼
- 优先权： KR20190093437 2019-07-31
- 主分类号： C12N15/81
- IPC分类号： C12N15/81 ; C07K14/395 ; C12N9/04 ; C12N9/88 ; C12N9/90 ; C12P5/02
摘要：
본발명은 C6 징크클러스터전사인자의활성이감소또는불활성화된, 스쿠알렌생산이증대된재조합미생물및 이를이용한스쿠알렌생산방법에관한것이다. 본발명의스쿠알렌생산이증대된재조합미생물은효모의대사경로내 탄소흐름(carbon-flux)을변화시켜, 기존비변형균주에비해고수율의스쿠알렌생산이가능하다.
摘要（英）：
The present invention relates to a recombinant microorganism in which the activity of a C6 zinc cluster transcription factor is reduced or inactivated, and to a method for producing squalene using the same. The recombinant microorganism having increased squalene production of the present invention changes carbon-flux in a metabolic pathway of a yeast, so that it is possible to produce squalene in a high yield compared to an existing unmodified strain.COPYRIGHT KIPO 2021