A modular filtration platform having at least one manifold head and at least one respective filter cartridge assembly. Each manifold head is connected to one another to establish a water flow in a series or parallel manner. Each filter cartridge assembly is releasably secured from rotation relative to the manifold head by a locking mechanism. An aperture on the filter cartridge assembly annular collar mates with a protruding resilient extension on either the manifold head or support bracket. Alternatively, an aperture on the filter cartridge assembly annular collar and an aperture on the manifold head annular collar mate with a protruding member from a locking ring extending through both apertures. An integrated sensor package may be integrated with the system for true managed water visible/audible indications and Wi-Fi interface to facilitate virtually instantaneous response times for filtration needs.