基本信息:
- 专利标题: 캡슐화된 유도성 맥락총 세포를 사용한 CNS 질환의 치료
- 专利标题(英):KR20180026669A - Treatment of cns disorders using encapsulated choroid plexus cell inducible
- 专利标题(中):用包封的可诱导冠状动脉细胞治疗中枢神经系统疾病
- 申请号:KR20177035998 申请日:2016-05-13
- 公开(公告)号:KR20180026669A 公开(公告)日:2018-03-13
- 优先权: US201562162390 2015-05-15
- 主分类号: A61K35/30
- IPC分类号: A61K35/30 ; A61K9/00 ; A61K9/48 ; A61K31/05 ; A61K31/185 ; A61K31/355 ; A61K31/375 ; A61K31/575 ; A61K38/06 ; A61P25/00
摘要:
하나이상의뇌척수액(CSF) 성분의변경된 (및특정구현예에서증가된) 수준을생성하도록유도된캡슐화된병원체비함유이종맥락총(CP) 세포를함유하는 CNS 이식된반투과성생체적합성캡슐을사용하는신경계질환및 장애의개선된치료와관련되는조성물및 방법이개시되어있다. 캡슐은면역학적거부, 염증또는이물질반응을유발하지않고현저하게 (이식후 16개월초과) 수명이긴 CP 세포에의해상승된 CSF 생산수준을유도할수 있도록개시된바와같이선택된다.
摘要(中):
的一个或多个脑脊髓液(CSF)的已经改变的分量的感应封装以产生(并且在某些实施例中增加)非2种脉络丛的水平含有病原体(CP)CNS植入使用含有细胞的生物相容胶囊半透神经障碍 以及涉及改善疾病治疗的组合物和方法。 如所描述的将被导致产生由免疫排斥升高CSF水平,显著而不引起炎症或异物反应(移植超过16个月后)寿命虽然CP细胞被选择胶囊。
摘要(英):
One or more of the cerebrospinal fluid (CSF) has changed the component of the induced encapsulated to produce (and increased in certain embodiments) level pathogen-containing non-two kinds of choroid plexus (CP) CNS implanted semipermeable neurological disorders using a biocompatible capsule containing the cells and there is associated with improved therapeutic compositions and methods are disclosed in the disorder. Capsules are selected as described to induce the production of CSF levels elevated by (16 months after implantation excess) it has a long lifetime CP cells significantly without causing an immunological rejection, inflammation or foreign body reaction.
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K35/00 | 含有其有不明结构的原材料或其反应产物的医用配制品 |
--------A61K35/02 | .来源于非生命物质的 |
----------A61K35/30 | ..神经;脑 |