基本信息:
- 专利标题： ＪＡＫ 억제제 및 관련 중간체 화합물의 제조 방법
- 专利标题（英）：KR20180011887A - Processes for Preparing JAK Inhibitors and Related Intermediate Compounds
- 申请号：KR20187002501 申请日：2010-01-14
- 公开(公告)号：KR20180011887A 公开(公告)日：2018-02-02
- 优先权： US14499109 2009-01-15
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07F7/10 ; C07F7/18
摘要：
본발명은화학식Ⅲ의키랄치환된피라졸릴피롤로[2,3-d]피리미딘, 및관련합성중간체화합물의제조방법에관한것이다. 상기키랄치환된피라졸릴피롤로[2,3-]피리미딘은염증성질환, 골수증식성장애, 및다른질환의치료를위한단백질티로신키나아제 (JAK)의야누스키나아제패밀리의억제제로서유용하다: [화학식Ⅲ]
摘要（英）：
The present invention relates to a process for the preparation of chiral substituted pyrazolyl-pyrrolo [2,3-d] pyrimidine, and related synthetic intermediate compound of formula Ⅲ. The chiral substituted pyrazolyl-pyrrolo [2,3-
d] pyrimidine are useful as inhibitors of Janus kinase family of inflammatory diseases, myeloproliferative disorders, and protein tyrosine kinase (JAK) for the treatment of other disorders:
Formula Ⅲ]
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D487/00 | 在稠环系中含有氮原子作为仅有的杂环原子的杂环化合物，不包含在C07D451/00至C07D477/00组中 |
| --------C07D487/02 | .在稠合系中含有两个杂环 |
| ----------C07D487/04 | ..邻位稠合系 |