基本信息:
- 专利标题： 접착성 헤파린과 콜라겐을 이용한 줄기세포의 배양방법
- 专利标题（英）：Method for culture of stem cells using co-immobilization of adhesive heparins and collagen
- 专利标题（中）：使用粘合剂肝素和胶原蛋白的共固定化来培养干细胞的方法
- 申请号：KR20160077827 申请日：2016-06-22
- 公开(公告)号：KR20180000098A 公开(公告)日：2018-01-02
- 发明人： 이해신 , 이미현 , 한용만 , 김영진
- 申请人： 한국과학기술원
- 申请人地址： 대전광역시 유성구 대학로 ***(구성동)
- 专利权人： 한국과학기술원
- 当前专利权人： 한국과학기술원
- 当前专利权人地址： 대전광역시 유성구 대학로 ***(구성동)
- 代理人： 이원희
- 优先权： KR20160077827 2016-06-22
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C08B37/00 ; C12N5/0735 ; C12N5/074
The present invention relates to a process for the preparation and culture method of the plate for stem cell cultures using an adhesive property of heparin and collagen, specifically catechol (cathchol) functional group, or pyrogallol (pyrogallol) functional groups conjugated (conjugation) heparin, and when culturing the stem cells in the plate for the stem cell was coated with collagen on the surface of the culture, the price significantly improve the adhesion rate of the cell culture surface inexpensive and enables the long term undifferentiated growth because it enables the mechanical sub-culturing, the adhesive heparin collagen and the culture of stem cells using the method can be effectively used as a mass culture of stem cells in a stable manner.