The invention of the silica nanoparticles functionalized with a chemical sensor for fluoride ion detected indicating the high selectivity and sensitivity, and relates to a method of manufacturing the same, and more particularly to a silyl ether with fluorescein isothiocyanate molecules are amino-molecule protected by a relates to chemical sensors for detecting fluoride ions, characterized in that the covalent bond to the surface.
Fluoride ion detected chemical sensor of the present invention, the method comprising the silylation of silica surface of the nanoparticles by silane having an amino group; The method comprising immobilizing a fluorescein isothiocyanate to said silylated nanoparticles; And tert- butyldimethylsilyl as being prepared by the steps of screen silyl chloride phenol group of the fluorescein isothiocyanate, the reaction of fluorescence of the fluoride ion "turn-on" indicates a high selectivity and sensitivity in the by silylation control the loading amount of the amino-molecular type and fluorescein isothiocyanate to the silica nanoparticle can be modified with a chemical sensor suitable for detecting a variety of ranges.