基本信息:
- 专利标题： 신규 IDO-1 저해제 및 이의 용도
- 专利标题（英）：New IDO-1 INHIBITOR AND USE THEREOF
- 专利标题（中）：IDO-1新型IDO-1抑制剂及其用途
- 申请号：KR1020150114127 申请日：2015-08-12
- 公开(公告)号：KR1020170019814A 公开(公告)日：2017-02-22
- 发明人： 김성욱 , 김홍우 , 유상희 , 허혜진 , 이홍범 , 김현욱
- 申请人： 이뮤노메트테라퓨틱스 인코포레이티드
- 申请人地址： JLABS at Texas Medical Center, **** Holcombe Blvd, Houston, TX *****, U.S.A.
- 专利权人： 이뮤노메트테라퓨틱스 인코포레이티드
- 当前专利权人： 이뮤노메트테라퓨틱스 인코포레이티드
- 当前专利权人地址： JLABS at Texas Medical Center, **** Holcombe Blvd, Houston, TX *****, U.S.A.
- 代理人： 손민
- 主分类号： C07D207/09
- IPC分类号： C07D207/09 ; C07D211/06 ; A61K31/40 ; A61K31/435 ; A61K31/18
The invention IDO- showing a superior effect on the IDO-inhibitor 1, and relates to their use, to inhibit further detail intracellular enzyme IDO (Indoleamine-2,3-dioxygenase) activity, inhibiting cancer metastasis and recurrence 1 inhibitors, to a method for their preparation and pharmaceutical compositions containing them as an active ingredient. IDO-1 inhibitor according to the present invention is to inhibit the less also excellent intracellular enzyme IDO enzyme activity in dosage compared to traditional drug, cancer metastasis and exhibits an excellent effect on cancer relapse suppressed, and thus cancer, breast cancer, stomach cancer, brain cancer, cancer can be usefully employed in the treatment of various cancers, such as colorectal cancer, lung cancer, skin cancer, blood cancer and liver cancer.
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D207/00 | 杂环化合物，含五元环，不与其他环稠合，带1个氮原子作为惟一的环杂原 |
| --------C07D207/02 | .只有氧或碳原子直接连在环氮原子上 |
| ----------C07D207/04 | ..环原子间或环原子与非环原子间无双键 |
| ------------C07D207/08 | ...带有被杂原子取代的烃基，连在环碳原子上 |
| --------------C07D207/09 | ....被非硝基氮原子取代的基 |