基本信息:
- 专利标题： 주사 이온전도 현미경
- 专利标题（英）：Scanning ion conductance microscopy
- 专利标题（中）：扫描离子导管显微镜
- 申请号：KR1020167028152 申请日：2015-03-10
- 公开(公告)号：KR1020160143683A 公开(公告)日：2016-12-14
- 发明人： 리차드슨,앤드류제임스
- 申请人： 오픈이오랩스 리미티드
- 申请人地址： Future Business Centre, Kings Hedges Road, Cambridge, CB* *HY, United Kingdom
- 专利权人： 오픈이오랩스 리미티드
- 当前专利权人： 오픈이오랩스 리미티드
- 当前专利权人地址： Future Business Centre, Kings Hedges Road, Cambridge, CB* *HY, United Kingdom
- 代理人： 특허법인 대아
- 优先权： GB14059000 2014-04-02; GB14041453 2014-03-10
- 国际申请： PCT/GB2015/050688 2015-03-10
- 国际公布： WO2015136260 2015-09-17
- 主分类号： G01Q60/44
- IPC分类号： G01Q60/44 ; G01Q10/06 ; G01Q60/02 ; G01Q60/60
A method of using SICM acquires the surface information of the sample is immersed in an electrolyte solution, immersing the portion of the first electrode immersed in an electrolyte solution for using a spread spectrum modulated signal to drive the ionic current in the electrolyte solution of the micro- step including in the pipette, and a second electrode of the control, the potential between the first and second electrodes that are external to a micropipette; Recording the ion current as control to the micro-pipette to move with respect to the stage supporting the sample; And an ion current, and from the calibration data, and determining a surface height profile of the sample. The potential can be controlled in accordance with a spread spectrum modulation signal. The micropipette motion may be in accordance with a micropipette, the first electrode and the AC mode, a pattern with a higher modulation frequency than the resonant frequency of the assembly of the first piezo actuator is arranged to control the z- axis motion of the micro-pipette.