基本信息:
- 专利标题： 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체
- 专利标题（英）：Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto
- 专利标题（中）：用于递送治疗药物的CYCLODEXTRIN-based聚合物
- 申请号：KR1020167024300 申请日：2003-09-04
- 公开(公告)号：KR1020160106223A 公开(公告)日：2016-09-09
- 发明人： 쳉,지안윤 , 데이비스,마크이. , 킨,케이티.
- 申请人： 인설트 테라페틱스, 인코퍼레이티드
- 申请人地址： **** Nina Street, Pasadena, CA ***** (US)
- 专利权人： 인설트 테라페틱스, 인코퍼레이티드
- 当前专利权人： 인설트 테라페틱스, 인코퍼레이티드
- 当前专利权人地址： **** Nina Street, Pasadena, CA ***** (US)
- 代理人： 강명구; 이경민
- 优先权： US60/408,855 2002-09-06; US60/422,830 2002-10-31; US60/451,998 2003-03-04
- 国际申请： PCT/US2003/027588 2003-09-04
- 国际公布： WO2004022099 2004-03-18
- 主分类号： A61K47/48
- IPC分类号： A61K47/48 ; A61K47/40 ; C08G63/91 ; C08B37/16
The present invention relates to new therapeutic compositions of cyclodextrin and pharmaceutical compositions thereof to retain the polymer compound designed as a carrier for small molecule therapeutic delivery. In particular, the therapeutic / life agent is cyclodextrin-covalently coupled to the polymer retention. These cyclodextrin-hold polymers improve drug stability and solubility of a small molecule therapeutic agent when used in vivo and reduces the toxic effects. Furthermore, by selecting a different target ligand linker groups, the polymer may be adjusted the delivery method of the therapeutic agent. The present invention also relates to a method of treatment with the therapeutic compositions described herein the subject. The present invention relates to a method for performing a pharmaceutical business comprising manufacturing, applying, distributing the kit in connection with the polymer compound described herein or further comprises a polymeric compound.
公开/授权文献:
- KR101857900B1 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체 公开/授权日：2018-05-14
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K47/00 | 以所用的非有效成分为特征的医用配制品，如载体、惰性添加剂 |
| --------A61K47/48 | .非有效成分被化学键键合到有效成分上，例如聚合物药物轭合物 |