基本信息:
- 专利标题： 벤조퓨란계 화합물 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 천식 예방 및 치료용 조성물
- 专利标题（英）：Compositions comprising benzofuran compounds or pharmaceutically acceptable salts thereof as an active ingredient for the prevention or treatment of asthma
- 专利标题（中）：包含苯佐芬化合物或药物可接受的盐作为预防或治疗哮喘的有效成分的组合物
- 申请号：KR1020150035047 申请日：2015-03-13
- 公开(公告)号：KR1020150107680A 公开(公告)日：2015-09-23
- 发明人： 이경 , 안경섭 , 오세량 , 신인식 , 권옥경 , 송혁환 , 신나래 , 허학진 , 전찬미
- 申请人： 한국생명공학연구원 , 동국대학교 산학협력단
- 申请人地址： ***, Gwahak-ro, Yuseong-gu, Daejeon, (***-***), Republic of Korea
- 专利权人： 한국생명공학연구원,동국대학교 산학협력단
- 当前专利权人： 한국생명공학연구원,동국대학교 산학협력단
- 当前专利权人地址： ***, Gwahak-ro, Yuseong-gu, Daejeon, (***-***), Republic of Korea
- 代理人： 이원희
- 优先权： KR1020140029658 2014-03-13
- 主分类号： A61K31/343
- IPC分类号： A61K31/343 ; A23L1/30 ; A61K9/20 ; A61K9/48
Airway of the present invention are benzofuran-type (benzofuran) compound or as a pharmaceutically acceptable salt thereof relates to a composition for asthma treatment and prevention containing as an active ingredient, benzofuran type (benzofuran) The compounds of the present invention induced asthma sensitization and suppress the infiltration of inflammatory cells effectively and control the immune response of Th2 type to inhibit the production of cytokines (interleukin-4, -5, -13) secreted because of this, and serum IgE and ovalbumin-specific IgE significantly reduce the generation and, because it reduces the inflammation in BAL fluid cell significantly, may be useful in the prevention and treatment of inflammatory diseases, including asthma or an inflammatory lung disease.
公开/授权文献:
- KR101718938B1 벤조퓨란계 화합물 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 천식 예방 및 치료용 조성물 公开/授权日：2017-03-23
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/33 | .杂环化合物 |
| ----------A61K31/335 | ..仅有氧作为环杂原子的，例如制霉色基素 |
| ------------A61K31/34 | ...有仅以1个氧作为环杂原子的五元环的，例如异山梨醇 |
| --------------A61K31/343 | ....与碳环稠合的，例如香豆满、丁呋洛尔、苯呋心安、氯苯呋醇、胺碘酮 |