基本信息:
- 专利标题： KRAS-관련 질환을 치료하기 위한 유기 조성물
- 专利标题（英）：Organic compositions to treat kras-related diseases
- 专利标题（中）：有机组合物治疗与KRAS相关的疾病
- 申请号：KR1020147033421 申请日：2013-04-30
- 公开(公告)号：KR1020150004414A 公开(公告)日：2015-01-12
- 发明人： 베텐코트,브라이언 , 밀스테인,스튜어트 , 토우드자르스카,이반카 , 맥도날드,얼 , 슐라바흐,마이클쥬니어 , 슈테그마이어,프랑크피. , 바르무트,마르쿠스 , 감파,칼리아니 , 휘스켄,디터 , 스텀프,마크 , 바일러,얀 , 자가니,자이납
- 申请人： 노파르티스 아게
- 申请人地址： Lichtstrasse **, CH-**** Basel, Switzerland
- 专利权人： 노파르티스 아게
- 当前专利权人： 노파르티스 아게
- 当前专利权人地址： Lichtstrasse **, CH-**** Basel, Switzerland
- 代理人： 양영준; 이상영
- 优先权： US61/641,588 2012-05-02
- 国际申请： PCT/US2013/038847 2013-04-30
- 国际公布： WO2013166004 2013-11-07
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K31/713 ; A61P35/00
This disclosure uses the RNAi agent to a therapeutically effective amount of KRAS KRAS- related diseases, such as solid or liquid without limitation, cancer, adenocarcinoma, colorectal cancer, advanced and / or metastatic colorectal cancer, colon cancer, lung cancer, non-small cell lung cancer and lung adenocarcinoma, acute myeloid cancer, bladder cancer, brain cancer, breast cancer, cervical cancer, endometrial cancer, gastric cancer, head and neck cancer, kidney cancer, leukemia, myelodysplastic syndrome, myeloid leukemia, liver cancer, melanoma, ovarian cancer, pancreatic cancer, prostate cancer, testicular cancer, , proliferative diseases, including thyroid cancer and heart-related to RNAi agents useful in methods for treating the skin (CFC) syndrome and Noonan syndrome, and related diseases and similar-face.
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K48/00 | 含有插入到活体细胞中的遗传物质以治疗遗传病的医药配制品；基因治疗 |