专利号KR1020130055006 | 라멜라 캡슐 및 이의 제조방법

专利标题： 라멜라 캡슐 및 이의 제조방법
专利标题（英）：Lamella capsule and formation method of the lamella capsule
专利标题（中）：LAMELLA CAPSULE和LAMELLA CAPSULE的形成方法
申请号：KR1020130055006 申请日：2013-05-15
公开(公告)号：KR1020140134937A 公开(公告)日：2014-11-25
发明人： 김도훈 , 신송석 , 임형준 , 조영석 , 남개원
申请人： (주)아모레퍼시픽
申请人地址： 서울특별시 중구 청계천로 *** (수표동)
专利权人： (주)아모레퍼시픽
当前专利权人： (주)아모레퍼시픽
当前专利权人地址： 서울특별시 중구 청계천로 *** (수표동)
代理人： 김영철; 임희택; 김 순 영
主分类号： A61K9/50
IPC分类号： A61K9/50 ; A61K47/30

摘要：

A capsule according to the present invention has a lamella structure including: a core having oil; and a outer shell having beta-1,3-glucan capturing the core, and therefore useful active ingredients such as vitamin, ceramide, and enzymes can be stably stored in the oil. Particularly, an active ingredient, which is susceptible to degeneration in an aqueous phase, such as aqueous vitamin, is stored in oil to allow the active ingredient to be stably stored. According to the preparation method of the present invention, a lamella structure having a core of a capsule including oil and an outer shell capturing the core can be easily prepared in a micro size only through a double nozzle structure consisting of a tube and a needle. Further, a size of the capsule or the core can be freely adjusted by only adjusting a diameter of the tube or the needle. Also, the capsule can be mass produced by using the method continuously.

摘要（中）：

根据本发明的胶囊具有薄片结构，包括：具有油的芯; 和具有捕获核心的β-1,3-葡聚糖的外壳，因此可以将有用的活性成分如维生素，神经酰胺和酶稳定地储存在油中。特别地，在水相中易于变性的活性成分如维生素水溶液储存在油中，以使活性成分稳定地储存。根据本发明的制备方法，仅通过由管和针组成的双喷嘴结构，可以以微小的尺寸容易地制备具有包含油的胶囊的芯和捕获芯的外壳的薄片结构。此外，通过仅调节管或针的直径，可以自由地调整胶囊或芯的尺寸。此外，可以通过连续使用该方法大量生产胶囊。

摘要（英）：

As a capsule according to the invention it is made of a lamellar structure consisting of a shell comprising a β-1,3- glucan, which collecting them and the core containing the oil, stable availability for active ingredients such as vitamins, ceramides, enzymes within the oil It can be kept. Particularly in the oil by keeping the active ingredient that is easily denatured in water, such as water-soluble vitamins can keep the active ingredient in a stable manner.
On the other hand, the manufacturing method according to the present invention can easily make only a double nozzle structure consisting of a lamellar structure of the shell that is trapping them and the capsule core comprising the oil to the tube and needle to the micro size. Further can freely adjust the size of the capsule or the core diameter of only size adjustment of the tube or needle, the capsule can be mass-produced by the above method using a continuously.

KR102002483B1 라멜라 캡슐 및 이의 제조방법 公开/授权日：2019-07-23

Espacenet

A	人类生活必需
--A61	医学或兽医学；卫生学
----A61K	医用、牙科用或梳妆用的配制品
------A61K9/00	以特殊物理形状为特征的医药配制品
--------A61K9/10	.分散液；乳剂
----------A61K9/50	..微型胶囊

发明公开 KR1020140134937A 라멜라 캡슐 및 이의 제조방법 审中-实审

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