基本信息:
- 专利标题： 손상 조직의 기능적 재생 촉진용 의약
- 专利标题（英）：Pharmaceuticals that promote functional regeneration of damaged tissues
- 专利标题（中）：促进损伤组织功能再生的药物
- 申请号：KR1020147023740 申请日：2007-10-30
- 公开(公告)号：KR1020140115373A 公开(公告)日：2014-09-30
- 发明人： 다마이가츠토 , 야마자키다케히코 , 가네다야스후미
- 申请人： 가부시키가이샤 제노믹스 , 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸
- 申请人地址： *-*-**, Saito-Asagi, Ibaraki-City, Osaka Japan
- 专利权人： 가부시키가이샤 제노믹스,고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸
- 当前专利权人： 가부시키가이샤 제노믹스,고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸
- 当前专利权人地址： *-*-**, Saito-Asagi, Ibaraki-City, Osaka Japan
- 代理人： 리앤목특허법인
- 优先权： JPJP-P-2006-293582 2006-10-30
- 国际申请： PCT/JP2007/071133 2007-10-30
- 国际公布： WO2008053892 2008-05-08
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/17 ; A61K48/00 ; A61K31/711 ; A61P17/00
The present inventors: 1) bone marrow-derived cells are mobilized in large quantities in transplantation skin, and 2) the mobilized bone marrow-derived cells are dermal fibroblasts, adipocytes, muscle cells, vascular endothelial cells, epidermal keratinocytes in the graft skin piece one that is also differentiated, that is the bone marrow, including the derived mesenchymal stem cells in the mobilized bone marrow-derived cells, and 3) is that mobilize bone marrow-derived mesenchymal stem cells in the peripheral blood in transplanted piece of skin in the necrotic tissue of the transplanted skin that is released HMGB1, HMGB2, HMGB3, 4) the HMGB1, HMGB2, HMGB3 tablets is to facilitate the separation and migration of the cultured mesenchymal stem cells in the bone marrow, 5) including HMGB1 to migration of bone marrow mesenchymal stem cells to the active substance that can be easily purified from the extract multiple organs, including the skin, brain, heart, and 6) of the active substance migration of bone marrow mesenchymal stem cells, weight easily in cultured cells What you can do, 7) it revealed that the heparin-column purified fraction of skin extract mobilize bone marrow-derived cells in large quantities during brain injury for the first time in the world.
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K38/00 | 含肽的医药配制品 |