基本信息:
- 专利标题： 암 치료 조성물 및 방법
- 专利标题（英）：Compositions and methods for treating cancer
- 专利标题（中）：用于治疗癌症的组合物和方法
- 申请号：KR1020137032528 申请日：2012-05-09
- 公开(公告)号：KR1020140048881A 公开(公告)日：2014-04-24
- 发明人： 산텐리차드제이. , 아이야르세라이.
- 申请人： 유니버시티 오브 버지니아 페이턴트 파운데이션
- 申请人地址： *** West Main Street, Suite ***, Charlottesville, VA *****, US
- 专利权人： 유니버시티 오브 버지니아 페이턴트 파운데이션
- 当前专利权人： 유니버시티 오브 버지니아 페이턴트 파운데이션
- 当前专利权人地址： *** West Main Street, Suite ***, Charlottesville, VA *****, US
- 代理人： 유미특허법인
- 优先权： US61/483,821 2011-05-09
- 国际申请： PCT/US2012/037056 2012-05-09
- 国际公布： WO2012154809 2012-11-15
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P35/00
The present invention provides a useful combination treatment for cancer, especially breast cancer. The present invention includes the steps of in various embodiments, a cancer patient, administered to the cancer patient an immunoconjugate comprising a monoclonal antibody moiety and the first cell apoptosis induced drug moiety linked to it in an effective amount; And a second apoptosis-inducing substance in an effective amount to provide a method for treating cancer comprising administering to said patient. Monoclonal antibody moiety of the immunoconjugate may function to target the HER2 receptor, for example of hormone-resistant breast cancer cells. When synergism is, was administered to patients suffering from breast cancer, such as a common molecular mechanism ( "Longitudinal Control") or other molecular mechanism ( "leveling") caused two cell suicide which act by the drug for hormone-resistant breast cancer, It may appear.
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |
| --------A61K39/395 | .抗体；免疫球蛋白；免疫血清，例如抗淋巴细胞血清 |