基本信息:
- 专利标题: 고분자 컨쥬게이트화된 단백질 마이셀
- 专利标题(英):Polymer conjugated protein micelles
- 专利标题(中):聚合物结合蛋白质细胞
- 申请号:KR1020137025324 申请日:2012-02-24
- 公开(公告)号:KR1020140048099A 公开(公告)日:2014-04-23
- 发明人: 페루말,오마타누피. , 포다랄라,새티쉬 , 아베리네니,란지스,쿠마
- 申请人: 사우스다코타주립대학
- 申请人地址: ADM ***, Box ****, Brookings, South Dakota *****-****, U. S. A.
- 专利权人: 사우스다코타주립대학
- 当前专利权人: 사우스다코타주립대학
- 当前专利权人地址: ADM ***, Box ****, Brookings, South Dakota *****-****, U. S. A.
- 代理人: 허용록
- 优先权: US61/446,931 2011-02-25
- 国际申请: PCT/US2012/026484 2012-02-24
- 国际公布: WO2012116272 2012-08-30
- 主分类号: A61K9/127
- IPC分类号: A61K9/127 ; A61K47/30 ; A61K31/704 ; C07K14/425 ; A61P35/00
The invention includes a method of preparing the compositions, and the micellar assemblies and its composition comprising a micellar assembly (micelle assemblies), micellar assembly. The invention also includes an amine Take the protein is conjugated to a polymer such as polyethylene glycol (PEG) chain, which may be used in the manufacture of the micellar assemblies. The invention includes a method of encapsulating a molecule using a conjugate further body (conjugates) of the present invention The micelles assembly to treatment of cancer, is to target a tumor, which will to be to reduce the toxicity of the drug in the body, increase the efficacy of the substance encapsulated in the body, to protect the encapsulated material against the decomposition It would like to, and increase the water solubility of the drug or other substance may be used for various applications.
公开/授权文献:
- KR101952599B1 고분자 컨쥬게이트화된 단백질 마이셀 公开/授权日:2019-05-22