基本信息:
- 专利标题： DGAT1 억제제로서 헤테로사이클릭 화합물
- 专利标题（英）：Heterocyclic compounds as dgat1 inhibitors
- 专利标题（中）：杂环化合物作为DGAT1抑制剂
- 申请号：KR1020137008599 申请日：2011-08-31
- 公开(公告)号：KR1020130114122A 公开(公告)日：2013-10-16
- 发明人： 샤르마,라지브 , 카담,키쇼르쿠마르시바지라오 , 자드하브,라빈드라드냔데브 , 칸드레,시바지사다시브 , 구프테,아몰
- 申请人： 피라말 엔터프라이지즈 리미티드
- 申请人地址： Piramal Tower, Ganpatrao Kadam Marg, Lower Parel, Mumbai *** ***, INDIA
- 专利权人： 피라말 엔터프라이지즈 리미티드
- 当前专利权人： 피라말 엔터프라이지즈 리미티드
- 当前专利权人地址： Piramal Tower, Ganpatrao Kadam Marg, Lower Parel, Mumbai *** ***, INDIA
- 代理人： 성낙훈
- 优先权： US61/379,760 2010-09-03
- 国际申请： PCT/IB2011/053810 2011-08-31
- 国际公布： WO2012029032 2012-03-08
- 主分类号： C07D271/10
- IPC分类号： C07D271/10 ; C07D263/34 ; A61K31/4245 ; A61P3/04
The invention in all stereoisomeric forms and tautomeric forms, a heterocyclic compound of the formula (1); And pharmaceutically acceptable salts thereof, medicaments, solvates, polymorphs (polymorphs), the carboxylic acid copper relates to a diploid (isosteres), and N- oxide. The invention also relates to a process for producing a cyclic said heterocyclic compound and pharmaceutical compositions containing them. The compounds and their pharmaceutical compositions are useful in the prevention and treatment of diseases and conditions mediated by acyltransferase (DGAT), especially DGAT1 acyl diacyl glycerol. The invention also by administering the compound or a pharmaceutical composition of a therapeutically effective amount, to a mammal in need provides a method of treating such diseases or disorders.
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D271/00 | 杂环化合物，含五元环，有两个氮原子和1个氧原子作为仅有的杂环原子 |
| --------C07D271/02 | .不和其他环稠合 |
| ----------C07D271/10 | ..1,3,4-二唑；氢化1,3,4-二唑 |