基本信息:
- 专利标题： 테트라넥틴 아포지방단백질 A-I, 이를 함유하는 지질 입자 및 이의 용도
- 专利标题（英）：Tetranectin-apolipoprotein a-i, lipid particles containing it and its use
- 专利标题（中）：四氯乙烯 - 阿波罗平蛋白A-I，含有它的脂质及其使用
- 申请号：KR1020137007879 申请日：2011-08-25
- 公开(公告)号：KR1020130059428A 公开(公告)日：2013-06-05
- 发明人： 바데르마틴 , 바에너모니카 , 핀게르레위르겐 , 코네르트울리히 , 마리쟝-루크 , 몰실케
- 申请人： 에프. 호프만-라 로슈 아게
- 申请人地址： 스위스 체하-**** 바젤 그렌짜체스트라쎄 ***
- 专利权人： 에프. 호프만-라 로슈 아게
- 当前专利权人： 에프. 호프만-라 로슈 아게
- 当前专利权人地址： 스위스 체하-**** 바젤 그렌짜체스트라쎄 ***
- 代理人： 제일특허법인
- 优先权： EP100089937 2010-08-30; EP101883924 2010-10-21
- 国际申请： PCT/EP2011/064602 2011-08-25
- 国际公布： WO2012028526 2012-03-08
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K9/16 ; A61K38/47 ; C07K14/775
In the present invention reports the lipid particles containing apo-lipoprotein, and phosphatidylcholine lipid, such as phospholipid, fatty acid or steroid lipids. In one embodiment the lipid particles will contain only a single apo lipoprotein. In one embodiment the lipid particle is formed of a single apo-lipoprotein, a phospholipid, a lipid and a detergent. Wherein said second lipid is phosphatidylcholine In one embodiment, wherein the second and the first phosphatidylcholine phosphatidylcholine is different from the esterification of one or two fatty acid residue or a fatty acid derivative to the glycerol backbone residues of the phosphatidylcholine. One apo lipoprotein in the embodiment of the variant thereof is selected from the apo lipoprotein having the SEQ ID NO: 1, 2, 6, 66 and 67 from more than 70% sequence has the amino acid sequence or selected and the selected sequence identity.
公开/授权文献:
- KR101631363B1 테트라넥틴 아포지방단백질 A-I, 이를 함유하는 지질 입자 및 이의 용도 公开/授权日：2016-06-17
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K9/00 | 以特殊物理形状为特征的医药配制品 |
| --------A61K9/10 | .分散液；乳剂 |
| ----------A61K9/127 | ..脂质体 |