基本信息:
- 专利标题： PDE10 억제제 및 관련 조성물 및 방법
- 专利标题（英）：Pde10 inhibitors and related compositions and methods
- 专利标题（中）：PDE10抑制剂及相关组合物和方法
- 申请号：KR1020127026545 申请日：2011-03-10
- 公开(公告)号：KR1020120135518A 公开(公告)日：2012-12-14
- 发明人： 컷쉘,네일,에스. , 게이그,제니퍼,린, , 윌러,토마스,네일, , 리틀,토마스,엘.
- 申请人： 오메로스 코포레이션
- 申请人地址： *** Elliott Avenue West, Seattle, Washington *****, U.S.A.
- 专利权人： 오메로스 코포레이션
- 当前专利权人： 오메로스 코포레이션
- 当前专利权人地址： *** Elliott Avenue West, Seattle, Washington *****, U.S.A.
- 代理人： 손민
- 优先权： US61/313,544 2010-03-12; US61/430,841 2011-01-07
- 国际申请： PCT/US2011/027927 2011-03-10
- 国际公布： WO2011112828 2011-09-15
- 主分类号： C07D417/10
- IPC分类号： C07D417/10 ; C07D413/10 ; A61K31/427 ; A61P25/00
Is described are compounds that inhibit PDE10, Also for various symptoms, e.g., (but not limited to), neurological disorders such as psychotic disorders, anxiety disorders, movement disorders and / or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, language, amnesia, facial palsy, cerebral polio, sleeping disorders, pain, toe rat syndrome, schizophrenia, delusional disorder, bipolar disorder, post traumatic stress disorder, drug induced psychosis, phobia , compulsive disorders, attention disorders, disruptive behavior disorders, autism, depression, dementia, provides a compound having a cognitive disorder, utility in the treatment of epilepsy, insomnia and multiple sclerosis doemda. Also be combined with a composition comprising a pharmaceutically acceptable carrier to compound is a process related to the use thereof for inhibiting PDE10 described in a warm-blooded animal in need thereof, of course.
公开/授权文献:
- KR101512548B1 PDE10 억제제 및 관련 조성물 및 방법 公开/授权日：2015-04-15
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D417/00 | 杂环化合物，含两个或更多个杂环、至少有1个环有氮原子和硫原子作为仅有的杂环原子，C07D415/00组不包含的 |
| --------C07D417/02 | .含有两个杂环 |
| ----------C07D417/10 | ..被含芳环的碳链连接的 |