基本信息:
- 专利标题: 외래 항원에 대한 숙주 내성을 파괴하기 위한 키메라 항원
- 专利标题(英):Chimeric antigens for breaking host tolerance to foreign antigens
- 专利标题(中):用于破坏对外国抗原的耐受性的CHIMERIC抗原
- 申请号:KR1020127022397 申请日:2004-08-06
- 公开(公告)号:KR1020120102167A 公开(公告)日:2012-09-17
- 发明人: 조지,라잔 , 타이렐,로른 , 누자임,안토인 , 왕,다쿤 , 마,알란
- 申请人: 팔라딘 랩스 아이엔씨
- 申请人地址: *** Alexis-Nihon Boulevard, Suite ***, Saint-Laurent, Quebec H*M *P*, Canada
- 专利权人: 팔라딘 랩스 아이엔씨
- 当前专利权人: 팔라딘 랩스 아이엔씨
- 当前专利权人地址: *** Alexis-Nihon Boulevard, Suite ***, Saint-Laurent, Quebec H*M *P*, Canada
- 代理人: 양영준; 김영
- 优先权: US60/493,449 2003-08-08
- 国际申请: PCT/CA2004/001469 2004-08-06
- 国际公布: WO2005014838 2005-02-17
- 主分类号: C07K14/005
- IPC分类号: C07K14/005 ; A61K39/12
There are compositions and methods for inducing an immune response to an antigen is disclosed herein. In particular, the compounds and methods are otherwise caused by an immune response against foreign antigens that are recognized by the host as "self" antigen and destroy the host tolerance to those antigens. The host's immune system, but to present the chimeric antigen comprises a target binding domain containing an antibody fragment, the immune response domain and a target binding domain enhances the immune response to foreign antigens or to be endured. Antigen-presenting cell is induced both by obtaining a chimeric antigen processing and presentation, the body fluid for the purpose of antigenicity and cellular immune response.
信息查询:
EspacenetIPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07K | 肽 |
------C07K14/00 | 具有多于20个氨基酸的肽;促胃液素;生长激素释放抑制因子;促黑激素;其衍生物 |
--------C07K14/005 | .来自病毒 |