基本信息:
- 专利标题: 핵자기공명 분광기를 이용한 동등생물의약품 구조의 비교 평가 방법
- 专利标题(英):Method for comparing and evaluating of the structure of biosimilars using nuclear magnetic resonance spectrometer
- 专利标题(中):使用核磁共振光谱仪比较和评估生物燃料结构的方法
- 申请号:KR1020100045240 申请日:2010-05-14
- 公开(公告)号:KR1020110125726A 公开(公告)日:2011-11-22
- 发明人: 박성혁 , 강선미
- 申请人: 인하대학교 산학협력단
- 申请人地址: ***, Inha-ro, Nam-gu, Incheon, (***-***), Republic of Korea
- 专利权人: 인하대학교 산학협력단
- 当前专利权人: 인하대학교 산학협력단
- 当前专利权人地址: ***, Inha-ro, Nam-gu, Incheon, (***-***), Republic of Korea
- 代理人: 이은철; 유완식
- 主分类号: G01N24/08
- IPC分类号: G01N24/08 ; G01N33/483 ; G01N33/15
摘要:
PURPOSE: A comparison evaluation method of equivalent creature drug structure, using a NMR spectroscopy is provided to use one-dimension first 1H-NMR or two-dimension 1H-13C HSQC spectrum about an equivalent creature drug structure without a pre-processing step. CONSTITUTION: A comparison evaluation method of equivalent creature drug structure is as follows. The creature drug sample is analyzed by using NMR spectroscopy. The one-dimension 1H-NMR spectrum is obtained from a sample which analyzes by using the NMR spectroscopy. The one-dimension 1H-NMR spectrum obtains data for 30 seconds ~3 minutes. Two dimension 1H-13C HSQC spectrum is obtained from the sample which analyzes by using the NMR spectroscopy. Two dimension 1H-13C HSQC spectrum obtains data for a ~30 minute and 3 hours.
摘要(中):
目的:提供等效生物药物结构的比较评估方法,使用NMR光谱法,使用关于等效生物药物结构的一维第一个1H-NMR或二维1H-13C HSQC光谱,无需预处理步骤。 构成:等效生物药物结构的比较评估方法如下。 通过使用NMR光谱分析生物药物样品。 从使用NMR光谱分析的样品获得一维1H-NMR光谱。 一维1H-NMR谱获得30秒〜3分钟的数据。 从使用NMR光谱分析的样品中获得二维1H-13C HSQC光谱。 二维1H-13C HSQC光谱获得约30分钟和3小时的数据。
公开/授权文献:
- KR101211971B1 핵자기공명 분광기를 이용한 동등생물의약품 구조의 비교 평가 방법 公开/授权日:2012-12-12
信息查询:
EspacenetIPC结构图谱:
G | 物理 |
--G01 | 测量;测试 |
----G01N | 借助于测定材料的化学或物理性质来测试或分析材料 |
------G01N24/00 | 利用核磁共振、电子顺磁共振或其他自旋效应来测试或分析材料 |
--------G01N24/08 | .利用核磁共振 |