基本信息:
- 专利标题: 관절내 연골 및 골조직 치유를 위한 동일계 시스템
- 专利标题(英):In situ system for intra-articular chondral and osseous tissue repair
- 专利标题(中):用于内科手术和OSSEOUS组织修复的原位系统
- 申请号:KR1020097015287 申请日:2007-12-21
- 公开(公告)号:KR1020090101273A 公开(公告)日:2009-09-24
- 发明人: 마티스버크하드
- 申请人: 라보라뜨와 메디동 소시에떼아노님
- 申请人地址: Enetriederstr. **, CH-**** Sarnen, Switzerland
- 专利权人: 라보라뜨와 메디동 소시에떼아노님
- 当前专利权人: 라보라뜨와 메디동 소시에떼아노님
- 当前专利权人地址: Enetriederstr. **, CH-**** Sarnen, Switzerland
- 代理人: 제일특허법인; 장성구
- 优先权: US60/871,554 2006-12-22
- 国际申请: PCT/IB2007/004067 2007-12-21
- 国际公布: WO2008078166 2008-07-03
- 主分类号: A61L27/24
- IPC分类号: A61L27/24 ; A61L27/54 ; A61L27/58 ; A61L31/16
摘要:
Disclosed is a device and method which provide a surgical therapy for in situ treatment and repair of intra-articular cartilage lesions and/or defects. The device is an implantable laminate cartilage repair patch which is bio-compatible and physiologically absorbable. The cartilage repair patch has a first outer cell occlusive layer; a second outer, cell porous layer adapted to be disposed proximate a subchondral bone wound site; and a cartilagenic matrix disposed between the first and second layers. The cartilagenic matrix is a sink for diffusion of autologous stem cells and includes chemical components promoting generation of hyaline-like cartilage in the presence of the autologous stem cells. The method of the present invention provides the autologous compositions, which when used in combination with the repair patch provides a therapeutic system to regenerate replacement hyaline-like intraarticular cartilage.
摘要(中):
公开了提供用于原位治疗和修复关节内软骨损伤和/或缺陷的手术治疗的装置和方法。 该装置是可植入的层压软骨修复贴片,其生物相容性和生理学吸收性。 软骨修复贴片具有第一外细胞封闭层; 第二外细胞多孔层,适于设置在软骨下骨创伤部位附近; 以及设置在第一和第二层之间的软骨基质。 软骨基质是自体干细胞扩散的沉淀物,包括在自体干细胞存在下促进产生透明样软骨的化学成分。 本发明的方法提供了自体组合物,当与修复贴片组合使用时,提供了再生替代性透明样关节内软骨的治疗系统。
公开/授权文献:
- KR101424308B1 관절내 연골 및 골조직 치유를 위한 동일계 시스템 公开/授权日:2014-08-01
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61L | 材料或物体消毒的一般方法或装置;空气的灭菌、消毒或除臭;绷带、敷料、吸收垫或外科用品的化学方面;绷带、敷料、吸收垫或外科用品的材料 |
------A61L27/00 | 假体材料或假体被覆材料 |
--------A61L27/02 | .无机材料 |
----------A61L27/22 | ..多肽或其衍生物 |
------------A61L27/24 | ...胶原 |